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Over Abundant Testosterone Decreases Brain Cells
High levels of testosterone
have been found to contribute to the loss of brains
cells. A recent study found that increased concentrated testosterone levels
lead to the self destruction of cells of the brain.
Studies have also shown
the increase also contributes to lower general IQ. Raised levels of
testosterone from steroid use or testosterone replacement therapy
(which is used to treat male menopause
) trigger neurodegenerative effects
on the brain.
Testosterone is the most powerful of the natural androgens
. A deep voice
and a beard are characteristics of the male sex that androgens stimulate
during development; they also strengthen muscle tone and bone mass.
High levels of testosterone can promote good health in men by lowering the
risks of high blood pressure or heart attack risk. But there are risky
behavior effects associated with high testosterone levels including
increased aggressiveness and smoking.
Steroid users have tendencies towards very aggressive behavior, leading
researchers to see the evidence of steroids effects on the brain.
Testosterone is a neuosteroid that can create changes at the cellular
level causing behavioral, mood and memory changes. These high levels
of testosterone can trigger programmed cell death of the nerve cells.
Apoptosis or cell death is necessary in biological changes, shown by
membrane instability, activation of the caspases and DNA fragmentation.
Over stimulation of the apoptotic function in the brain's neurons exposed
to testosterone has also been connected to a variety of neurological illnesses,
including Alzheimer's diseases and Huntington disease.
The treatment of neuroblastoma cells with highly concentrated levels of
testosterone for a short time periods causes a decrease in cell existence
by the stimulation of a cell death program.
The overstimulation of the apoptotic function in brain neurons witnessed
during exposure to testosterone has in the past also been associated with
a number of neurological illnesses, such as Alzheimer's disease and
Huntington disease.
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